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Surgical Science
WHAT'S NEW


Dr. Schmidt Is a Guest on NPR Science Friday

Ann Marie Schmidt, MD, was a guest on NPR’s “Talk of the Nation: Science Friday” on December 8, 2006, discussing her research on “the master switch for inflammation,” the RAGE cell-surface receptor. RAGE is involved in many chronic illnesses including diabetes complications and heart disease. Listen to the broadcast on the Talk of the Nation website. Click here to go to the Columbia Division of Surgical Science website.

Pfizer Contracts to Test and Market RAGE-Antagonist Drugs


Ann Marie Schmidt, MD

The cell-surface molecule RAGE (Receptor for Advanced Glycation Endproducts) contributes significantly to many ills, including cancer, heart disease, Alzheimer's disease, diabetes complications such as nephropathy, and a host of immune-related disorders. For Ann Marie Schmidt, MD, Chief of the Department of Surgery's Division of Surgical Science, who has been studying RAGE for over a decade, this molecule's ability to trigger such a wide variety of disorders has revealed an unexpectedly unified picture of chronic disease and how it might be medically reversed. After more than 15 years leading basic research on the molecule, Dr. Schmidt is now seeing her efforts pay off in development of therapies for people.


Highlight on Translational Research—RAGE

Translational research is all the rage at Columbia University Medical Center. Not all the rage, perhaps, but work by the Division of Surgical Science on the Receptor for Advanced Glycation Endproducts (RAGE) represents a vitally important segment of translational research currently underway at this institution.


Publication News

The Division of Surgical Science is collaborating with the Division of Abdominal Organ Transplantation on research studies that explore the limits of liver regeneration. Initial findings were published in the February 7, 2005 issue of The Journal of Experimental Medicine.

Investigator Grant News

Collaborative Grants


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